Tesamorelin

Tesamorelin is a synthetic peptide that acts as a growth hormone-releasing hormone (GHRH) analog. It is primarily used to reduce excess abdominal fat in people with HIV-associated lipodystrophy.

How It Works

Tesamorelin stimulates the pituitary gland to release growth hormone (GH), which helps regulate metabolism and fat distribution. Unlike direct GH injections, tesamorelin encourages the body to produce its own growth hormone, potentially leading to a more natural hormonal balance.

Potential Benefits

• Fat Reduction: Primarily used to reduce visceral fat (deep abdominal fat) in people with HIV-related lipodystrophy.

• Improved Metabolism: May enhance insulin sensitivity and glucose metabolism.

• Cognitive Benefits: Some research suggests it may support brain function in aging individuals.

• Muscle Maintenance: May help preserve lean body mass.

Potential Risks & Side Effects

• Increased blood sugar levels (may worsen or trigger diabetes in some individuals)

• Joint pain & swelling

• Carpal tunnel syndrome symptoms (numbness/tingling in hands)

• Nausea, headaches, or flushing

• Increased risk of cancer growth (theoretical concern since GH promotes cell growth)

• Hypersensitivity reactions (rare)

Use in Bodybuilding & Anti-Aging

Though some off-label users take tesamorelin for fat loss, anti-aging, or muscle gain, it is not FDA-approved for these purposes. It differs from other GH-boosting peptides because it does not suppress natural GH production, making it a preferred option for some seeking hormone optimization.