Retitrutide

Retatrutide is an investigational triple hormone receptor agonist that activates GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors. It is being studied primarily for weight loss and type 2 diabetes.

Potential Benefits of Retatrutide:

1. Significant Weight Loss – Early trials show it leads to more weight loss than semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound).

2. Improved Blood Sugar Control – Helps regulate glucose levels, beneficial for type 2 diabetes.

3. Reduced Appetite – Slows digestion and reduces hunger, helping with calorie intake reduction.

4. Increased Energy Expenditure – Unlike semaglutide and tirzepatide, it may also boost metabolism.

5. Cardiovascular Benefits – May lower blood pressure and improve cholesterol levels.

6. Potential Fat Loss Over Muscle Loss – Some evidence suggests it helps preserve lean muscle mass compared to other weight loss drugs.